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6 Causes of Pancreatitis Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders. Illustration of the pancreas. Source: MedicineNet Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013 REFERENCES References 1/7 What is pancreatitis? Pancreatitis is inflammation of the pancreas. The pancreas is a large gland located in your abdomen that produces enzymes and hormones that help break down your food so the body can digest it properly. When the pancreas becomes inflamed, these digestive enzymes become active before they leave the pancreas, and they damage the pancreatic tissue. There are two forms of pancreatitis: acute and chronic. Acute pancreatitis occurs suddenly over a short time period. Chronic pancreatitis usually occurs after the acute stage, when inflammation continues. There are several causes of pancreatitis.


6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
Illustration of the pancreas.
Source: MedicineNet
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

What is pancreatitis?

Pancreatitis is inflammation of the pancreas. The pancreas is a large gland located in your abdomen that produces enzymes and hormones that help break down your food so the body can digest it properly.
When the pancreas becomes inflamed, these digestive enzymes become active before they leave the pancreas, and they damage the pancreatic tissue.
There are two forms of pancreatitis: acute and chronic. Acute pancreatitis occurs suddenly over a short time period. Chronic pancreatitis usually occurs after the acute stage, when inflammation continues.
There are several causes of pancreatitis.


6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
Example of gallstones.
Source: BigStock
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

Gallstones

Most commonly, acute pancreatitis is caused by gallstones. It is estimated that up to 40% of all cases of pancreatitis are caused by gallstones.
The gallbladder stores bile that is secreted by the liver, which aids in digestion. Gallstones occur when cholesterol and other substances found in bile form stones. When these stones pass from the gallbladder into the bile duct they can become stuck.
When this occurs, it can affect the enzymes produced by the pancreas. In a healthy person, these pancreatic enzymes aid in digestion. When there is a blockage caused by a gallstone, these enzymes start to damage the pancreatic tissue instead.

 

6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
A man drinking a bottle of alcohol alone.
Source: 123RF
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

Heavy Alcohol Use

The second most common cause of acute pancreatitis is heavy alcohol use, accounting for about 30% of acute pancreatitis cases.
While it is not fully understood how heavy alcohol use contributes to pancreatitis, it is believed that alcohol leads to accumulation of digestive enzymes, and allows the enzymes to cause pancreatic damage. It also creates and imbalance of protein and bicarbonates in the pancreas, which does not allow the organ to drain properly.
Alcohol-induced pancreatitis is usually seen in people who drink habitually for years, but it can also happen after a binge drinking session.


6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
Prescription medication bottle and pills.
Source: Veer
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

Medications

While gallstones and heavy alcohol use cause most cases of pancreatitis, medications also can cause a small percentage of cases.
Medications known to cause pancreatitis include some antibiotics, immunosuppressants, high blood pressure medications, medicines to treat inflammatory bowel disease, diuretics, corticosteroids, estrogen, diabetes medications, medicines used to treat seizure disorders, general anesthetics, and antidepressants.
If you develop pancreatitis, make sure your doctor knows all medications you are taking. Never change your dose or stop taking a prescribed medication without first consulting your doctor.


6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
Print out of cholesterol and blood screen results.
Source: iStockPhoto
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

3 Less Common Causes of Pancreatitis

Less common causes of pancreatitis include infections, high blood triglycerides (fats), and hereditary disorders.
In about 20% of cases, the cause for pancreatitis is unknown. This is called idiopathic pancreatitis.
Acute pancreatitis can turn into chronic pancreatitis, when the inflammation continues and the tissue of the pancreas becomes scarred.

6 Causes of Pancreatitis

Learn symptoms of pancreatitis, and what causes it, including gallstones, alcohol use, medications, infections, high blood triglycerides (fats), and hereditary disorders.
Print out of cholesterol and blood screen results.
Source: iStockPhoto
Reviewed by John P. Cunha, DO, FACOEP on August 15, 2013

3 Less Common Causes of Pancreatitis

Less common causes of pancreatitis include infections, high blood triglycerides (fats), and hereditary disorders.
In about 20% of cases, the cause for pancreatitis is unknown. This is called idiopathic pancreatitis.
Acute pancreatitis can turn into chronic pancreatitis, when the inflammation continues and the tissue of the pancreas becomes scarred.